Gene regulatory networks
Categories:
Classic papers
J Zhu et al. An integrative genomics approach to the reconstruction of gene networks in segregating populations. Cytogenet Genome Res 105:363–374 (2004)
J Faith et al. Large-Scale Mapping and Validation of E. coli Transcriptional Regulation from a Compendium of Expression Profiles. PLOS Biol 5:e8 (2007).
V Huynh-Thu et al. Inferring Regulatory Networks from Expression Data Using Tree-Based Methods. PLOS One 5:e12776 (2010).
See also a recent perspective on network inference in Nature: Smart software untangles gene regulation in cells
An integrative genomics approach to the reconstruction of gene networks in segregating populations
Figure 1
Hierarchical clustering of the data set in the gene expression and eQTL dimensions
Figure obtained from full text on EuropePMC.
Figure 3
Sub-networks associated with Hsd11b1
Figure obtained from full text on EuropePMC.
Large-Scale Mapping and Validation of E. coli Transcriptional Regulation from a Compendium of Expression Profiles
Software
Figure 1
Overview of the approach
Figure obtained from full text on EuropePMC.
Figure 2
The CLR algorithm
Figure obtained from full text on EuropePMC.
Figure 5
Experimental Validation of Inferred Regulatory Interactions
Figure obtained from full text on EuropePMC.
Inferring Regulatory Networks from Expression Data Using Tree-Based Methods
Software
Figure 1
GENIE3 procedure
Figure obtained from full text on EuropePMC.
Figure 4
Precision-Recall curves for the E. coli network
Figure obtained from full text on EuropePMC.