Genetics of gene expression

The GTEx Consortium atlas of genetic regulatory effects across human tissues

Figure 1

Concepts

• Genome-wide association studies (GWAS)
• Expression quantitative trait locus (eQTL)
• cis vs trans eQTLs

Figure 2

Concepts

• Linkage disequilibrium (LD)
• Stepwise regression

Figure 3

Concepts

• Statistical finemapping
• ENCODE in GWAS

Figure 4

Concepts

• Enrichment in functional annotations
• Mediation analysis

Figure 5

Concepts

• Mendelian randomization (MR)

Figure 6

Concepts

• Logistic regression

Figure 7