A preprint of our paper “Graph-based data integration predicts long-range regulatory interactions across the human genome” is available on arXiv and bioRxiv. In this paper we use graph-based methods to combine multiple datasets of open chromatin and gene expression information in matching cell types from the ENCODE project to predict long-range interactions between regulatory elements in the human genome and their target genes. Predicted interactions between can be browsed here.
We have reopened the vacancy for this and this PhD position, more details here. Closing date for applications 25 April.
We contributed to a paper by Sabine Jägle and Andreas Hecht on “Silencing of the EPHB3 tumor suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer” published in PNAS. Congrats to Sabine and Andreas!
We contributed to a paper by Johan Björkegren and Josefin Skogsberg from the Cardiovascular Genomics group on “Plasma cholesterol–induced lesion networks activated before regression of early, mature, and advanced atherosclerosis”, published in PLoS Genetics. Congrats to Josefin who lead the study!
We have a vacancy for a Research Fellow to join the group from 1st May 2014. See the Roslin website or NatureJobs for the job advert. Closing date for applications 26th March 2014.
Applications are invited for PhD projects in the division of Genetics & Genomics, including two in our lab. Deadline for applications 3rd Feb 2014. More details and application procedure here.
Our paper about the software tool kruX for performing millions of non-parametric ANOVA (Kruskal-Wallis) tests at once using matrix-multiplication methods has been published by BMC Bioinformatics. The final version is also available from the arXiv.
A warm welcome to Siddharth who joins the lab to work on a joint project with Liam Morrison to study host-pathogen interactions in trypanosome infections.
A PhD position is available to study the genetic control of human vascular senescence, in collaboration with the lab of Albert Tenesa. For more information, see the vacancy. Closing date for applications 10 January 2014!
A PhD position is available to study the systems biology of host-parasite interactions in trypanosome infections, in collaboration with the lab of Liam Morrison. For more information, see the vacancy. Closing date for applications 10 January 2014!